Description

2-Chloro-4-(3,5-Dimethyl-1H-Pyrazol-1-Yl)-Pyrimidine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its crucial role in the synthesis of complex molecules, particularly in medicinal chemistry where it serves as a key precursor for active pharmaceutical ingredients (APIs). Chemical manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty chemical sectors need this material for developing new therapeutic agents and high-performance chemical products.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its bioactive pyrimidine-pyrazole hybrid structure.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Fine Chemical Production: A key intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Chloro-4-(3,5-Dimethyl-1H-Pyrazol-1-Yl)-Pyrimidine
CAS No.	52476-66-1
Molecular Formula	C9H9ClN4
Molecular Weight	208.65 g/mol
Synonyms	2-Chloro-4-(3,5-dimethylpyrazol-1-yl)pyrimidine; 4-(3,5-Dimethyl-1H-pyrazol-1-yl)-2-chloropyrimidine; 2-Chloro-4-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine; Pyrimidine, 2-chloro-4-(3,5-dimethyl-1H-pyrazol-1-yl)-; 1-(2-Chloropyrimidin-4-yl)-3,5-dimethyl-1H-pyrazole; 2-Chloro-4-(3,5-dimethylpyrazol-1-yl)pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(3,5-Dimethyl-1H-Pyrazol-1-Yl)-Pyrimidine is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.