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6-Bromo-L-Tryptophan CAS NO 52448-17-6
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CAS No.:52448-17-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
6-Bromo-L-Tryptophan is a halogenated derivative of the essential amino acid L-tryptophan, serving as a critical chiral building block in advanced organic synthesis. This compound matters for its role in the development of novel pharmaceuticals, particularly in the creation of peptide-based drugs and enzyme inhibitors. Researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries need it for its utility in medicinal chemistry and as a precursor for more complex bioactive molecules.
Application
- Pharmaceutical Intermediate: Key chiral synthon for the research and development of new therapeutic agents, including protease inhibitors and neuroactive compounds.
- Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate brominated tryptophan residues, modifying peptide properties for drug discovery.
- Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme-substrate interaction research.
- Agrochemical Development: Potential intermediate in the synthesis of novel, biologically active crop protection agents.
- Academic & R&D: Employed in university and institutional laboratories for methodological development in organic and medicinal chemistry.
- Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
Basic Information
| Product Name | 6-Bromo-L-Tryptophan |
| CAS No. | 52448-17-6 |
| Molecular Formula | C₁₁H₁₁BrN₂O₂ |
| Molecular Weight | 283.12 g/mol |
| Synonyms | (S)-2-Amino-3-(6-bromo-1H-indol-3-yl)propanoic acid; L-6-Bromotryptophan; 6-Bromo-L-tryptophan; 6-Br-Trp; 6-Bromo-L-Trp; 6-Bromotryptophan; (S)-6-Bromotryptophan; 6-Bromo-L-tryptophane |
| EINECS | Contact for details |
Quality Control
Our 6-Bromo-L-Tryptophan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing specific batch results are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥98.0% |
| Chiral Purity (HPLC) | ≥99.0% (L-Isomer) |
| Loss on Drying | ≤1.0% |
| Heavy Metals | ≤20 ppm |
| Residue on Ignition | ≤0.1% |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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