Description

Valyl Adenylate is a crucial biochemical intermediate, specifically an aminoacyl adenylate, formed during the activation of the amino acid valine for protein synthesis. This compound matters significantly in research and development for studying the fundamental mechanisms of translation, enzyme kinetics, and tRNA charging. It is primarily needed by biochemical researchers, pharmaceutical developers, and diagnostic manufacturers working in enzymology, molecular biology, and the development of novel antibiotics or metabolic pathway inhibitors.

Application

• Biochemical Research: Essential substrate for studying aminoacyl-tRNA synthetase (ValRS) activity, enzyme specificity, and the fidelity of protein biosynthesis.
• Enzyme Inhibition Studies: Used as a reference compound or competitive inhibitor in the development and screening of novel antimicrobial agents that target bacterial protein synthesis.
• Diagnostic Reagent Development: Serves as a key component in enzymatic assays designed to detect and quantify specific aminoacyl-tRNA synthetase activity in clinical or research samples.
• Metabolic Pathway Analysis: A critical intermediate for investigating valine metabolism and its incorporation into proteins within cellular and in vitro systems.
• Pharmaceutical Intermediates: Potential use as a building block or precursor in the synthesis of more complex nucleotide-based therapeutics or prodrugs.
• Educational & Reference Standard: Provides a high-purity standard for academic teaching and analytical method validation in life sciences.

Basic Information

Product Name	Valyl Adenylate
CAS No.	52435-65-1
Molecular Formula	C16H23N7O8P
Molecular Weight	472.38 g/mol
Synonyms	L-Valyl adenylate; Adenosine 5'-(L-valine) monophosphate; Valine adenylate; Valyl-AMP; L-Valyl-AMP; 5'-O-[N-(L-Valyl)sulfamoyl]adenosine (deprotonated form); Aminoacyl adenylate (valine-specific); ValRS intermediate
EINECS	Contact for details

Quality Control

Our Valyl Adenylate is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a dry atmosphere before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, DMSO; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.