Description

[Des-Gly10, D-Ala6]-Lh-Rh Ethylamide Acetate Hydrate is a synthetic peptide analog of luteinizing hormone-releasing hormone (LHRH). This compound is a valuable research-grade biochemical tool used to study and modulate the hypothalamic-pituitary-gonadal axis. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in endocrinology, reproductive biology, and neuropeptide research.

Application

• Biomedical Research: As a reference standard and active agent in studies of gonadotropin secretion and receptor binding.
• Pharmacological Studies: For investigating the structure-activity relationships (SAR) of LHRH analogs and their effects.
• Assay Development: Used in the development and validation of immunoassays (e.g., ELISA, RIA) and bioassays for LHRH activity.
• Drug Discovery: Serves as a key intermediate or lead compound in the development of novel therapeutic agents targeting hormonal pathways.
• Academic & Clinical Research: Fundamental tool for exploring reproductive physiology, neuroendocrinology, and potential therapeutic applications.

Basic Information

Product Name	[Des-Gly10, D-Ala6]-Lh-Rh Ethylamide Acetate Hydrate
CAS No.	52435-06-0
Molecular Formula	C56H78N16O12 • xC2H4O2 • yH2O
Molecular Weight	~1183.34 (anhydrous free base)
Synonyms	Des-Gly10, D-Ala6-LHRH Ethylamide Acetate; [Des-Gly10, D-Ala6]-LHRH EA; D-Ala6, Des-Gly10-LHRH Ethylamide; Luteinizing Hormone-Releasing Hormone (6-D-Alanine, 10-Glycinamide) Ethylamide; LHRH Analog (D-Ala6, Des-Gly10-NHEt); Gonadorelin (6-D-Ala, 10-des-Gly-NHEt) analog; pGlu-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt Acetate
EINECS	Contact for details

Quality Control

Our [Des-Gly10, D-Ala6]-Lh-Rh Ethylamide Acetate Hydrate is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency suitable for research applications. Quality is verified through a comprehensive suite of analytical techniques. Certificates of Analysis (COA) detailing purity, identity, and content are available upon request for every batch shipped.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (Content)	≥ 97.0% (on anhydrous, solvent-free basis)
Water Content (KF)	≤ 8.0%
Acetate Content (IC)	3.0 - 8.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.