Description

L-Oxazepam is a high-purity, single enantiomer of the benzodiazepine derivative oxazepam, distinguished by its specific stereochemistry. This compound is of significant interest in advanced pharmaceutical research and development, particularly for studying stereoselective pharmacological effects. It serves as a critical chiral intermediate or reference standard for laboratories and manufacturers focused on neuropharmacology, analytical method development, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for quality control and analytical method validation (e.g., HPLC, GC-MS) in pharmaceutical testing.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key chiral building block in the research-scale synthesis of specialized benzodiazepine-based active ingredients.
• Metabolite Studies: Employed in pharmacological and toxicological research to investigate the metabolism and pharmacokinetics of oxazepam and related compounds.
• Biochemical Research: Utilized as a ligand in studies targeting GABA-A receptors to understand binding affinity and stereoselectivity.
• Forensic Analysis: Acts as a high-purity calibrant or control in forensic toxicology for the accurate identification and quantification of benzodiazepines.

Basic Information

Product Name	L-Oxazepam
CAS No.	52432-54-9
Molecular Formula	C15H11ClN2O2
Molecular Weight	286.71 g/mol
Synonyms	(S)-Oxazepam; (-)-Oxazepam; Levoxazepam; (3S)-7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one; 7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one (S-enantiomer); L-7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one
EINECS	Contact for details

Quality Control

Our L-Oxazepam CAS NO 52432-54-9 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting standards for research and development purposes. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.