Description

H-Phe-Nhnh2 is a specialized hydrazide derivative of phenylalanine, a key building block in organic synthesis and pharmaceutical research. This compound is valued for its role as a versatile intermediate in the synthesis of peptide mimetics, enzyme inhibitors, and other bioactive molecules. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on creating novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of peptide-based drugs, protease inhibitors, and other active pharmaceutical ingredients (APIs).
• Bioconjugation & Labeling: Used in the preparation of affinity probes, diagnostic reagents, and antibody-drug conjugates (ADCs) due to its reactive hydrazide group.
• Chemical Biology Research: Serves as a tool compound for studying enzyme mechanisms and developing novel biochemical assays.
• Peptidomimetic Synthesis: Enables the construction of non-natural peptide analogs with enhanced stability and biological activity.
• Material Science: Employed in the development of functional polymers and smart materials with specific molecular recognition properties.
• Academic & Industrial R&D: A fundamental reagent for exploratory chemistry in universities and corporate research centers worldwide.

Basic Information

Product Name	H-Phe-Nhnh2
CAS No.	52386-52-4
Molecular Formula	C9H13N3O2
Molecular Weight	195.22 g/mol
Synonyms	L-Phenylalanine hydrazide; (S)-2-Amino-3-phenylpropanehydrazide; Phenylalanine hydrazide; Fmoc-Phe-NHNH2 (protected form); H-Phe-NHNH2•HCl (salt form); Phe-NHNH2; 2-Amino-3-phenylpropionic acid hydrazide
EINECS	Contact for details

Quality Control

Our H-Phe-Nhnh2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, chiral purity, and identification by spectroscopic methods. Certificates of Analysis (COA) are available for every batch and provided upon request, supporting compliance with cGMP and other relevant regulatory guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.