Description

4(1H)-Pyrimidinone, 6-Amino-2-Chloro- (9Ci) is a heterocyclic organic compound belonging to the pyrimidinone class, serving as a versatile and high-value pharmaceutical intermediate. Its core value proposition lies in its role as a critical building block for synthesizing complex active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables targeted molecular design. This compound is essential for R&D chemists and production specialists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of antiviral and anticancer drug candidates, particularly those targeting nucleotide metabolism.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging its heterocyclic core for biological activity.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and as a scaffold for probing nucleotide-binding sites.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Material Science Research: Investigated as a potential monomer or functional component in the development of advanced organic electronic materials.

Basic Information

Product Name	4(1H)-Pyrimidinone, 6-Amino-2-Chloro- (9Ci)
CAS No.	52386-11-5
Molecular Formula	C4H4ClN3O
Molecular Weight	145.55 g/mol
Synonyms	6-Amino-2-chloro-4(1H)-pyrimidinone; 2-Chloro-6-amino-4-pyrimidinol; 2-Chloro-6-aminopyrimidin-4(1H)-one; 6-Amino-2-chloro-4-hydroxypyrimidine; 2-Chloro-6-amino-4(1H)-pyrimidinone; 6-Amino-2-chloro-4-pyrimidinol; 2-Chloro-6-aminopyrimidin-4-ol; 6-Amino-2-chloro-4(3H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 4(1H)-Pyrimidinone, 6-Amino-2-Chloro- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after initial use to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.