Description

H-Pro-Tyr-NH2 HCl is a protected dipeptide building block, specifically the hydrochloride salt of H-Pro-Tyr-NH2. This compound is a crucial intermediate in solid-phase peptide synthesis (SPPS), enabling the controlled construction of complex peptide sequences. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and fine chemical manufacturers developing therapeutic peptides, research biochemicals, and high-value specialty compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid derivative for the sequential assembly of custom peptide chains.
• Pharmaceutical Intermediate: Serves as a critical building block in the research and development of novel peptide-based therapeutics.
• Biochemical Research: Used in studies involving proline-tyrosine motifs, enzyme substrates, or receptor ligands.
• Fine Chemical Production: Employed in the synthesis of specialized peptides for diagnostic, cosmetic, or nutraceutical applications.
• Custom Peptide Services: A fundamental raw material for CROs and CDMOs offering bespoke peptide synthesis.

Basic Information

Product Name	H-Pro-Tyr-NH2 HCl
CAS No.	52329-46-1
Molecular Formula	C14H20N3O4 • HCl
Molecular Weight	331.79 g/mol (Free base: 294.33)
Synonyms	L-Prolyl-L-tyrosinamide hydrochloride; Pro-Tyr-NH2 • HCl; H-Pro-Tyr-NH2 • HCl; L-Pro-L-Tyr-NH2 hydrochloride; N-[(Benzyloxy)carbonyl]-L-prolyl-L-tyrosinamide hydrochloride (related protected form); Z-Pro-Tyr-NH2 HCl (related protected form); Prolyltyrosinamide hydrochloride; 52329-46-1
EINECS	Contact for details

Quality Control

Our H-Pro-Tyr-NH2 HCl is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and batch-to-batch consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.