Description

Valyl-Prolyl-Glycyl-Valyl-Glycine is a synthetic pentapeptide with the sequence Val-Pro-Gly-Val-Gly. This compound is a valuable biochemical building block and research tool, particularly in the study of collagen structure and peptide-based materials. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and cosmetic industries for applications ranging from drug discovery to advanced biomaterials. The product is supplied as a high-purity material to ensure reliable and reproducible results in demanding applications.

Application

• Biochemical Research: Used as a model peptide for studying collagen-like triple-helix formation, protein folding, and peptide stability.
• Pharmaceutical Development: Serves as an intermediate or a reference standard in the synthesis and analysis of novel therapeutic peptides and peptidomimetics.
• Cosmetic Science: Investigated for potential use in anti-aging and skin-repair formulations due to its structural similarity to collagen fragments.
• Biomaterial Engineering: Acts as a building block for creating synthetic extracellular matrices, hydrogels, and other bioactive scaffolds.
• Enzyme Substrate Studies: Employed in assays to study the activity and specificity of proteolytic enzymes like collagenases and matrix metalloproteinases (MMPs).
• Academic & Institutional Research: A key reagent for universities and research institutes focusing on biophysics, structural biology, and medicinal chemistry.

Basic Information

Product Name	Valyl-Prolyl-Glycyl-Valyl-Glycine
CAS No.	52231-42-2
Molecular Formula	C22H36N6O7
Molecular Weight	496.56 g/mol
Synonyms	Val-Pro-Gly-Val-Gly; VPGVG; VPGVG Peptide; Pentapeptide VPGVG; (Val-Pro-Gly-Val-Gly); L-Valyl-L-prolyl-glycyl-L-valylglycine; Poly(VPGVG); GVGVP
EINECS	Contact for details

Quality Control

Our Valyl-Prolyl-Glycyl-Valyl-Glycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral purity checks, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.