Description

(-)-n-[(S)-2-Hydroxy-3-Mercapto(1)Propionyl]-L-Tyr-L-Ile-L-Gln-L-Asn-L-Cys(1)-L-Pro-L-Leu-Gly-Nh2 is a synthetic, nonapeptide derivative with a complex structure featuring a thiol-containing side chain. This compound is of significant interest in advanced pharmaceutical research, particularly for its potential role as a biochemical tool or a precursor in peptide-based drug discovery. It is primarily utilized by research institutions and pharmaceutical development laboratories engaged in studying enzyme inhibitors, receptor ligands, and novel therapeutic peptides. The CAS number for this compound is 52194-62-4.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis of novel peptide-based therapeutics targeting specific biological pathways.
• Biochemical Tool Compound: Used in in vitro studies to investigate enzyme-substrate interactions, inhibition mechanisms, and signal transduction processes.
• Proteomics and Peptide Chemistry: Employed as a building block for constructing more complex peptide structures or for studying structure-activity relationships (SAR).
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry, biochemistry, and molecular biology.
• Reference Standard: Acts as a high-purity calibrant for analytical methods such as HPLC and LC-MS in quality control laboratories.

Basic Information

Item	Detail
Product Name	(-)-n-[(S)-2-Hydroxy-3-Mercapto(1)Propionyl]-L-Tyr-L-Ile-L-Gln-L-Asn-L-Cys(1)-L-Pro-L-Leu-Gly-Nh2
CAS No.	52194-62-4
Molecular Formula	C44H66N12O15S2
Molecular Weight	1051.2 g/mol
Synonyms	Nonapeptide derivative; H-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (modified); Mercaptopropionyl-modified peptide; [Cys(1), Cys(1)]-Nonapeptide; L-Tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide (cyclic); Thiol-functionalized nonapeptide; Research peptide 52194-62-4; S-[(2S)-2-Hydroxy-3-mercapto-1-oxopropyl] derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. For this research-grade peptide, quality is assured through advanced analytical techniques including HPLC for purity assessment and Mass Spectrometry for identity confirmation, meeting the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, this material should be stored under an inert atmosphere (e.g., argon or nitrogen) at a controlled temperature of -20°C or below for long-term stability. For short-term use, store desiccated at 2-8°C. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.