Description

Lhrh, Des-Tyr(5)- CAS NO 52186-43-3 is a synthetic peptide analog of luteinizing hormone-releasing hormone (LHRH) with a specific modification. This compound is a critical research-grade biochemical used for studying neuroendocrine pathways and receptor interactions. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on endocrinology and peptide-based therapeutic development.

Application

• Biochemical Research: Fundamental studies on the structure-activity relationships (SAR) of LHRH and its analogs.
• Endocrinology Studies: Investigation of pituitary hormone release mechanisms and gonadotropin regulation.
• Pharmaceutical Development: Serves as a key reference standard and intermediate in the development of novel peptide therapeutics and diagnostic agents.
• Receptor Binding Assays: Used as a ligand in competitive binding experiments to characterize LHRH receptor affinity and specificity.
• In Vitro Bioassays: Evaluation of biological activity in cell-based systems to model hormonal responses.

Basic Information

Product Name	Lhrh, Des-Tyr(5)- CAS NO 52186-43-3
CAS No.	52186-43-3
Molecular Formula	C52H74N16O12
Molecular Weight	1107.3 g/mol
Synonyms	Des-Tyr5-LHRH; Luteinizing Hormone-Releasing Hormone (5-De-L-tyrosine); LHRH (Des-Tyr5); LH-RH (5-De-L-tyrosine); Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 (Des-Tyr5); Gonadorelin (5-De-L-tyrosine); Factrel (5-De-L-tyrosine) analog; Luliberin (5-De-L-tyrosine)
EINECS	Contact for details

Quality Control

Our Lhrh, Des-Tyr(5)- is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, MS, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.