Description

5-Bromo-1H,5H-Pyrimidine-4,6-Dione is a halogenated pyrimidine derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its reactive bromine substituent and the uracil-like dione structure, enabling precise molecular modifications. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, active pharmaceutical ingredients (APIs), and other fine chemicals. Its utility extends to agrochemical research and materials science as a specialized precursor.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel nucleoside analogs and potential antiviral or anticancer agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex heterocyclic systems.
• Biochemical Research: Potential use in studying enzyme inhibition and as a modified base in oligonucleotide synthesis for probing biological mechanisms.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Bromo-1H,5H-Pyrimidine-4,6-Dione
CAS No.	52176-13-3
Molecular Formula	C4H3BrN2O2
Molecular Weight	190.98 g/mol
Synonyms	5-Bromobarbituric Acid; 5-Bromo-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Bromomalonylurea; 5-Bromopyrimidine-4,6-diol; Bromobarbituric Acid; NSC 401564
EINECS	Contact for details

Quality Control

Our 5-Bromo-1H,5H-Pyrimidine-4,6-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.