Description

5-(3-Trifluoromethyl-Phenyl)-Furan-2-Carbaldehyde is a high-value fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. Its core value lies in the unique combination of the furan ring's reactivity and the trifluoromethyl group's lipophilicity and metabolic stability, enabling the development of novel compounds with enhanced properties. This intermediate is critically needed by pharmaceutical and agrochemical R&D teams for creating active ingredients, as well as by material scientists developing specialty polymers and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in therapeutic areas requiring fluorinated molecules for improved bioavailability and target binding.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Functional Material Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up services in fine chemical production.

Basic Information

Product Name	5-(3-Trifluoromethyl-Phenyl)-Furan-2-Carbaldehyde
CAS No.	52130-30-0
Molecular Formula	C12H7F3O2
Molecular Weight	240.18 g/mol
Synonyms	3'-(Trifluoromethyl)[1,1'-biphenyl]-2-carboxaldehyde; 5-[3-(Trifluoromethyl)phenyl]-2-furancarboxaldehyde; 2-Furaldehyde, 5-[3-(trifluoromethyl)phenyl]-; 5-(3-Trifluoromethylphenyl)furan-2-carbaldehyde; 5-(m-Trifluoromethylphenyl)-2-furaldehyde; α,α,α-Trifluoro-m-tolylfurfural; [3-(Trifluoromethyl)phenyl]-2-furancarboxaldehyde
EINECS	Contact for details

Quality Control

Our 5-(3-Trifluoromethyl-Phenyl)-Furan-2-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.