Description

4-(2-Chloro-6-Methylpyrimidin-4-Yl)Morpholine CAS NO 52026-43-4 is a high-purity, synthetically valuable pyrimidine derivative characterized by its morpholine and chloro-methyl substituents. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, enabling the development of novel active ingredients. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating targeted molecular libraries and scaling up production processes.

Application

This specialized intermediate is designed for high-value synthesis applications where precise molecular architecture is paramount.

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products.
• Chemical Synthesis: Versatile precursor for constructing complex heterocyclic compounds in medicinal chemistry.
• R&D and Process Development: Essential for route scouting, optimization, and scale-up studies in process chemistry.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds.
• Library Synthesis: Used in combinatorial chemistry to generate diverse compound libraries for biological screening.

Basic Information

Product Name	4-(2-Chloro-6-Methylpyrimidin-4-Yl)Morpholine
CAS No.	52026-43-4
Molecular Formula	C9H12ClN3O
Molecular Weight	213.66 g/mol
Synonyms	4-(2-Chloro-6-methylpyrimidin-4-yl)morpholine; 2-Chloro-6-methyl-4-morpholinopyrimidine; Morpholine, 4-(2-chloro-6-methyl-4-pyrimidinyl)-; 4-(2-Chloro-6-methyl-4-pyrimidinyl)morpholine; 4-(2-Chloro-6-methylpyrimidin-4-yl)morpholine; 52026-43-4; 2-Chloro-4-morpholino-6-methylpyrimidine; 4-Morpholino-2-chloro-6-methylpyrimidine
EINECS	Contact for details

Quality Control

Our production of 4-(2-Chloro-6-Methylpyrimidin-4-Yl)Morpholine adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthesis work. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for advanced pharmaceutical applications and can provide material manufactured under quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.