Description

4-Pyrimidinol is a versatile heterocyclic organic compound that serves as a crucial building block in advanced chemical synthesis. Its unique pyrimidine core structure makes it a valuable intermediate for the development of pharmaceuticals, agrochemicals, and specialty materials. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality intermediates for their synthesis pipelines.

Application

The pyrimidine scaffold is fundamental to numerous active compounds, making 4-Pyrimidinol a key synthetic intermediate. Its primary applications include:

• Pharmaceutical Intermediate: Core building block for the synthesis of various drug candidates, including antiviral, anticancer, and central nervous system (CNS) active agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that utilize pyrimidine chemistry.
• Material Science Research: Serves as a precursor for developing organic ligands, coordination polymers, and other advanced functional materials.
• Biochemical Research: Employed in studies involving nucleotide analogs and enzyme inhibitors due to its structural similarity to nucleic acid bases.
• Fine Chemical Production: A versatile starting material for synthesizing dyes, pigments, and other specialty chemicals.

Basic Information

Product Name	4-Pyrimidinol
CAS No.	51953-18-5
Molecular Formula	C4H4N2O
Molecular Weight	96.09 g/mol
Synonyms	4-Hydroxypyrimidine; Pyrimidin-4-ol; 4(1H)-Pyrimidinone; 4-Pyrimidinol; 4-Hydroxy-1,3-diazine; 1H-Pyrimidin-4-one; 4-Pyrimidinol (base); 4-Pyrimidone; 4-Hydroxypyrimidine (enol form)
EINECS	Contact for details

Quality Control

Our 4-Pyrimidinol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.