Description

Ethyl 2,4-Dichloropyrimidine-5-Carboxylate is a versatile and high-purity pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites, which enable efficient, multi-step functionalization for creating complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and kinase inhibitor drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as semiconductors and light-emitting compounds.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and R&D Laboratories: Used in medicinal chemistry and process chemistry research for method development and exploring new chemical entities.

Basic Information

Item	Detail
Product Name	Ethyl 2,4-Dichloropyrimidine-5-Carboxylate
CAS No.	51940-64-8
Molecular Formula	C7H6Cl2N2O2
Molecular Weight	221.04 g/mol
Synonyms	2,4-Dichloro-5-pyrimidinecarboxylic acid ethyl ester; Ethyl 2,4-dichloro-5-pyrimidinecarboxylate; 5-Carbethoxy-2,4-dichloropyrimidine; 2,4-Dichloropyrimidine-5-carboxylic acid ethyl ester; 5-Ethoxycarbonyl-2,4-dichloropyrimidine; Ethyl 2,4-dichloro-5-pyrimidinecarboxylic acid; 51940-64-8; NSC 403058
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2,4-Dichloropyrimidine-5-Carboxylate is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure high purity, consistency, and traceability. Our standard grade meets specifications suitable for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.