Description

H-Pro-Ile-Oh CAS NO 51926-51-3 is a high-purity dipeptide derivative, specifically L-Prolyl-L-Isoleucine, serving as a critical building block in advanced organic synthesis and pharmaceutical research. This compound is valued for its role in constructing complex peptide structures and studying biochemical pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery, proteomics, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs) and therapeutic agents.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Peptide Synthesis: An essential building block in solid-phase and solution-phase peptide synthesis (SPPS) for creating custom peptides.
• Drug Discovery: Employed in high-throughput screening and medicinal chemistry programs to explore structure-activity relationships (SAR).
• Cosmetic Peptides: A potential ingredient in the formulation of advanced cosmetic peptides for skincare applications.
• Academic & Industrial R&D: Serves as a valuable reagent in university laboratories and corporate R&D centers for chemical and biological investigations.

Basic Information

Product Name	H-Pro-Ile-Oh
CAS No.	51926-51-3
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	L-Prolyl-L-isoleucine; Pro-Ile; H-Pro-Ile-OH; L-Pro-L-Ile; Prolylisoleucine; 2-[(2S)-1-[(2S,3S)-2-Amino-3-methylpentanoyl]pyrrolidine-2-carboxylic acid; (S)-2-((S)-2-Amino-3-methylpentanamido)pyrrolidine-1-carboxylic acid; H-L-Pro-L-Ile-OH
EINECS	Contact for details

Quality Control

Our H-Pro-Ile-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]²⁰D: -70° to -80° (c=1 in H₂O)
Water Content (KF)	≤1.0%
Heavy Metals	≤10 ppm
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.