Description

3-Chloro-L-Alanine Hydrochloride is a halogenated derivative of the amino acid alanine, supplied as its hydrochloride salt for enhanced stability and handling. This compound serves as a versatile chiral building block and a key intermediate in the synthesis of more complex bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications ranging from drug discovery to the development of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitor design.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate reaction mechanisms and enzyme specificity.
• Agrochemical Synthesis: Employed as a building block for creating advanced herbicides and pesticides with targeted activity.
• Peptide Chemistry: Incorporated into custom peptides to study structure-activity relationships or to introduce specific functionalities.
• Metabolite Analog Production: Serves as a precursor for synthesizing analogs of natural metabolites for biological evaluation.
• Fine Chemical Manufacturing: Acts as a key intermediate in the multi-step synthesis of specialty chemicals and complex organic compounds.

Basic Information

Item	Details
Product Name	3-Chloro-L-Alanine Hydrochloride
CAS No.	51887-89-9
Molecular Formula	C3H7ClNO2 • HCl
Molecular Weight	170.01 g/mol
Synonyms	(S)-2-Amino-3-chloropropanoic acid hydrochloride; L-3-Chloroalanine hydrochloride; (S)-3-Chloroalanine HCl; 3-Chloro-L-alanine HCl; 3-Chloroalanine hydrochloride; β-Chloro-L-alanine hydrochloride; NSC 163038; 3-Chloroalanine HCl salt
EINECS	Contact for details

Quality Control

Our 3-Chloro-L-Alanine Hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.