Description

Asp-Arg-Val-Tyr-Ile-His-Pro CAS NO 51833-78-4 is a high-purity heptapeptide sequence, also known as Angiotensin I (1-7), which plays a significant role in the renin-angiotensin system (RAS). This compound is a critical research standard and a key intermediate for the development of cardiovascular and metabolic disorder therapeutics. It is essential for pharmaceutical R&D, biochemical research, and the production of reference materials for diagnostic assays.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the study of the renin-angiotensin system and drug discovery for hypertension and heart failure.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate ACE2 activity and the metabolic pathways of angiotensin peptides.
• Diagnostic Manufacturing: Employed as a calibrator or antigen in the production of immunoassay kits for measuring angiotensin peptide levels in clinical and research settings.
• Peptide Synthesis: Acts as a crucial building block for the solid-phase or solution-phase synthesis of longer, modified peptide analogs for structure-activity relationship (SAR) studies.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to study receptor binding, signal transduction, and the physiological effects of Angiotensin-(1-7) on various tissue types.

Basic Information

Product Name	Asp-Arg-Val-Tyr-Ile-His-Pro
CAS No.	51833-78-4
Molecular Formula	C41H62N14O11
Molecular Weight	899.02 g/mol
Synonyms	Angiotensin I (1-7); Angiotensin-(1-7); Asp-Arg-Val-Tyr-Ile-His-Pro-OH; DRVYIHP; H-Asp-Arg-Val-Tyr-Ile-His-Pro-OH; UNII-4NM6GOI5QJ; ACE2 substrate
EINECS	Contact for details

Quality Control

Our Asp-Arg-Val-Tyr-Ile-His-Pro is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.