Description

Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-Oh is a synthetic nonapeptide, also known as Saralasin Acetate, which functions as a competitive angiotensin II receptor antagonist. This compound is of significant interest in biochemical and pharmacological research due to its role in modulating the renin-angiotensin system. It is primarily utilized by research institutions and pharmaceutical developers focusing on cardiovascular research, hypertension studies, and the development of peptide-based therapeutic agents.

Application

• Biochemical Research: Used as a standard or tool compound in studies investigating the renin-angiotensin-aldosterone system (RAAS) and its physiological effects.
• Pharmacological Studies: Serves as a reference angiotensin II antagonist in receptor binding assays and functional bioassays to evaluate new drug candidates.
• Cardiovascular Research: Employed in experimental models to study hypertension, vascular tone, and cardiac function.
• Peptide Chemistry Reference: Acts as a high-purity intermediate or analytical standard for method development in peptide synthesis and analysis.
• Academic & Institutional Labs: Utilized in university and research institute settings for teaching and advanced research projects in endocrinology and peptide biology.

Basic Information

Product Name	Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-Oh
CAS No.	51833-69-3
Molecular Formula	C49H70N14O11
Molecular Weight	1007.2 g/mol
Synonyms	Saralasin Acetate; [Sar1, Ala8]-Angiotensin II; 1-Sarcosine-8-alanine-angiotensin II; Sar-Arg-Val-Tyr-Val-His-Pro-Ala-OH; Saralasin; NSC 332007; Angiotensin II Antagonist; [Sar1,Ala8]Ang II
EINECS	Contact for details

Quality Control

Our Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-Oh is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content (AAA)	≥ 80.0%
Solubility	Soluble in water, acetic acid; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.