Description

D-Erythro-3,4-Dihydroxyphenylserine is a specialized, high-purity amino acid derivative of significant interest in advanced pharmaceutical research and synthesis. This compound serves as a critical chiral building block and a key intermediate in the development of active pharmaceutical ingredients (APIs) targeting neurological and cardiovascular systems. It is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on producing sophisticated therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex Active Pharmaceutical Ingredients (APIs), particularly those with catecholamine-like activity.
• Neurological Research: Used in biochemical studies and the development of potential therapeutics for neurological disorders, including Parkinson's disease and certain forms of hypotension.
• Enzymology Studies: Serves as a substrate or inhibitor in research involving aromatic L-amino acid decarboxylase and other related enzymes.
• Asymmetric Synthesis: Employed as a starting material or resolving agent in the preparation of other enantiomerically pure compounds due to its defined stereochemistry.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	D-Erythro-3,4-Dihydroxyphenylserine
CAS No.	51829-98-2
Molecular Formula	C9H11NO5
Molecular Weight	213.19 g/mol
Synonyms	D-DOPS; D-Erythro-DOPS; (2R,3S)-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid; L-Threo-DOPS (enantiomer); Nordihydroxynorephedrine carboxylic acid derivative; 3,4-DiHPP; (-)-Three-Dihydroxyphenylserine (related isomer); Erythro enantiomer of Droxidopa precursor
EINECS	Contact for details

Quality Control

Our D-Erythro-3,4-Dihydroxyphenylserine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as argon or nitrogen in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% (D-Erythro)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.