Description

Ketoleucine Calcium Salt Dihydrate is a specialized calcium complex of the branched-chain keto acid derivative, 4-methyl-2-oxopentanoic acid. This compound is valued for its role as a stable, bioavailable source of calcium and a metabolic precursor in advanced biochemical and nutritional applications. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, nutraceutical, and high-purity chemical synthesis sectors.

Application

• Pharmaceutical Intermediates: Serves as a key chiral building block or precursor in the synthesis of specialized active pharmaceutical ingredients (APIs).
• Metabolic Research: Used in biochemical and nutritional studies investigating branched-chain amino acid (BCAA) metabolism, ketone body utilization, and energy pathways.
• Nutraceutical Formulations: Incorporated into advanced dietary supplements targeting muscle metabolism, energy production, and calcium supplementation.
• Cell Culture Media: Acts as a component in specialized cell culture formulations to study cellular metabolism under specific nutrient conditions.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical and food testing laboratories.
• Chemical Synthesis: Utilized in organic synthesis for the preparation of complex molecules requiring the ketoleucine moiety.

Basic Information

Product Name	Ketoleucine Calcium Salt Dihydrate
CAS No.	51828-95-6
Molecular Formula	C12H18CaO6 • 2H2O
Molecular Weight	328.35 g/mol (anhydrous basis)
Synonyms	4-Methyl-2-oxopentanoic acid calcium salt dihydrate; Calcium 4-methyl-2-oxovalerate dihydrate; Calcium ketoleucinate dihydrate; Calcium α-ketoisocaproate dihydrate; KIC calcium salt dihydrate; 2-Oxoisocaproic acid calcium salt dihydrate; (4-Methyl-2-oxopentanoato)calcium dihydrate
EINECS	Contact for details

Quality Control

Our Ketoleucine Calcium Salt Dihydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis, to ensure it meets stringent purity specifications. Certificates of Analysis (COA) documenting all test results are provided to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	9.0% - 12.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
pH (5% solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.