Description

Boc-Val-Gly-Ome is a protected dipeptide building block widely used in solid-phase peptide synthesis (SPPS). This compound is essential for the controlled elongation of peptide chains, offering orthogonal protection for the N-terminal valine residue. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing therapeutic peptides, peptide hormones, and diagnostic agents. Its reliable quality ensures consistent coupling efficiency and high-purity final products.

Application

• Pharmaceutical Intermediates: Key building block for the synthesis of complex therapeutic peptides and peptide-based drugs.
• Solid-Phase Peptide Synthesis (SPPS): Used in Fmoc/t-Bu and Boc/Bzl strategies for the sequential addition of amino acids.
• Bioconjugation: Serves as a precursor for creating peptide tags, linkers, and probes used in antibody-drug conjugates (ADCs) and diagnostics.
• Research & Development: Essential reagent in academic and industrial R&D for exploring new peptide structures and biological activities.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Custom Peptide Services: A fundamental raw material for CROs and CDMOs offering bespoke peptide manufacturing.

Basic Information

Product Name	Boc-Val-Gly-Ome
CAS No.	51803-69-1
Molecular Formula	C₁₃H₂₄N₂O₅
Molecular Weight	288.34 g/mol
Synonyms	Boc-Val-Gly-OMe; N-(tert-Butoxycarbonyl)-L-valylglycine methyl ester; (2S)-2-[(2-{[(tert-Butoxy)carbonyl]amino}-3-methylbutanoyl)amino]acetic acid methyl ester; Methyl N-[(tert-butoxy)carbonyl]-L-valylglycinate; Boc-L-Val-Gly-OMe; Boc-Val-Gly-Methyl Ester; tert-Butyloxycarbonylvalylglycine Methyl Ester
EINECS	Contact for details

Quality Control

Our Boc-Val-Gly-Ome is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	-40° to -44° (c=1 in MeOH)
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.