Description

Insulin, Des(Hexapeptide)(B25-30)-Ala(B23)- is a specifically modified insulin analog, a key intermediate in advanced pharmaceutical research and development. This compound is crucial for studying insulin's structure-activity relationships and for the development of novel therapeutic agents targeting metabolic disorders. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in endocrinology research, diabetes drug discovery, and peptide-based therapeutic innovation.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis and study of novel insulin analogs and peptide-based therapeutics.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies and receptor binding assays to understand insulin signaling pathways.
• Drug Discovery Programs: A key building block for medicinal chemists developing next-generation treatments for diabetes and related metabolic syndromes.
• Academic Research: Employed in university and institutional labs for fundamental studies on protein structure, folding, and hormone action.
• Process Development: Used in the scale-up and optimization of manufacturing processes for insulin-related biopharmaceuticals.

Basic Information

Item	Detail
Product Name	Insulin, Des(Hexapeptide)(B25-30)-Ala(B23)-
CAS No.	51798-58-4
Molecular Formula	C250H381N65O74S6
Molecular Weight	~5575.5 g/mol
Synonyms	Des-(B25-B30)-[AlaB23]-Insulin; [AlaB23]Des-(B25-B30)-Insulin; Insulin (human) Des-(B25-B30)-AlaB23-; Insulin analog (B23-Ala, des-B25-30); Truncated Insulin Analog; Insulin Intermediate; Insulin Derivative; Research Insulin Peptide
EINECS	Contact for details

Quality Control

Our Insulin, Des(Hexapeptide)(B25-30)-Ala(B23)- is produced under stringent conditions to ensure the highest standards of purity and consistency, suitable for sensitive research applications. Each batch is characterized using advanced analytical techniques including HPLC, MS, and peptide mapping. Certificates of Analysis (COA) detailing purity, identity, and related substances are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); containers should be allowed to equilibrate to room temperature before opening to prevent condensation. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content (UV)	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.