Description

L-Histidine Monohydrobromide is the hydrobromide salt form of the essential amino acid L-Histidine. This high-purity derivative is critical for applications requiring enhanced solubility and stability in formulations. It serves as a vital building block and functional ingredient for manufacturers in the pharmaceutical, nutraceutical, and biochemical research sectors.

Application

• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and peptide drugs.
• Cell Culture Media: An essential amino acid component in mammalian and microbial cell culture formulations.
• Dietary Supplements & Clinical Nutrition: Incorporated into parenteral nutrition solutions and specialized amino acid supplement blends.
• Biochemical Research: A key reagent in enzymatic studies, protein structure analysis, and metabolic pathway research.
• Cosmetic & Personal Care: Utilized in advanced skincare formulations for its potential skin-conditioning properties.

Basic Information

Product Name	L-Histidine Monohydrobromide
CAS No.	51783-76-7
Molecular Formula	C6H10N3O2 • HBr
Molecular Weight	232.08 g/mol
Synonyms	L-Histidine HBr; Histidine Hydrobromide; (S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid hydrobromide; H-His-OH•HBr; L-Histidine, hydrobromide; Histidine monohydrobromide; L-Histidine hydrobromide salt; L-Histidine HBr monohydrate (common hydrate form)
EINECS	257-402-8

Quality Control

Our L-Histidine Monohydrobromide is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets stringent purity and identity criteria. We can supply material compliant with various pharmacopeial standards (e.g., USP, EP) upon request. A comprehensive Certificate of Analysis (COA) is provided with each batch to guarantee traceability and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.5% - 101.5% (on anhydrous basis)
Specific Rotation	+8.5° to +10.5° (c=2 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.