Description

3-(Trifluoromethylthio)Benzaldehyde is a versatile fluorinated aromatic aldehyde building block, distinguished by the presence of a trifluoromethylthio (-SCF₃) substituent. This compound is valued for its unique electronic properties and its role as a key intermediate in the synthesis of advanced materials and bioactive molecules. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides, where the -SCF₃ group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with tailored electronic and optical properties.
• Fluorine Chemistry Research: An essential building block for academic and industrial research focused on introducing sulfur-containing fluorinated motifs into organic molecules.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	3-(Trifluoromethylthio)Benzaldehyde
CAS No.	51748-27-7
Molecular Formula	C₈H₅F₃OS
Molecular Weight	206.18 g/mol
Synonyms	m-(Trifluoromethylthio)benzaldehyde; 3-(Trifluoromethylsulfanyl)benzaldehyde; Benzaldehyde, 3-[(trifluoromethyl)thio]-; α-Oxo-m-(trifluoromethylthio)toluene; 3-(Trifluoromethylmercapto)benzaldehyde; 3-SCF₃-Benzaldehyde; 3-Trifluoromethylthiobenzaldehyde
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethylthio)Benzaldehyde is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert gas atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.