Description

Nicotinamide N1-Propylsulfonate is a specialized, water-soluble derivative of nicotinamide (Vitamin B3) designed for enhanced stability and bioavailability. This compound is critical for formulators seeking to incorporate the metabolic benefits of niacin into stable, non-flushing applications. It serves as a key intermediate and active ingredient for manufacturers in the cosmetic, nutraceutical, and pharmaceutical industries, where its unique sulfonate group offers superior solubility and skin penetration properties.

Application

• Cosmetic & Skincare Formulations: Used as a stable source of niacinamide in anti-aging serums, moisturizers, and brightening creams for its skin barrier repair and anti-inflammatory properties.
• Dietary Supplements & Nutraceuticals: Incorporated into advanced supplement blends as a non-flushing, bioavailable form of Vitamin B3 to support cellular energy metabolism and NAD+ precursor activity.
• Pharmaceutical Intermediates: Serves as a crucial building block in the synthesis of more complex drug molecules targeting metabolic disorders.
• Biochemical Research: Utilized as a reagent in enzymatic studies and metabolic pathway research due to its role in NAD/NADP cofactor systems.
• Hair Care Products: Formulated into shampoos and treatments to improve scalp health and promote hair strength.
• Functional Food & Beverage Fortification: Applied for nutrient fortification in products requiring high water solubility and stability of Vitamin B3.

Basic Information

Product Name	Nicotinamide N1-Propylsulfonate
CAS No.	51652-08-5
Molecular Formula	C9H12N2O4S
Molecular Weight	244.27 g/mol
Synonyms	Nicotinamide Propylsulfonate; 1-Propylsulfonic Acid Nicotinamide Salt; Niacinamide Propyl Sulfonate; Vitamin B3 Propylsulfonate; 3-Carbamoylpyridin-1-ium-1-ylpropane-1-sulfonate; PNPS; N1-Propylsulfonic Acid Nicotinamide Inner Salt
EINECS	Contact for details

Quality Control

Our Nicotinamide N1-Propylsulfonate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for high-purity applications. Certificates of Analysis (COA) documenting full specifications are available upon request. We support compliance with cGMP, ISO, and REACH requirements for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
pH (10% solution)	5.0 - 7.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.