Description

2,4-Dihydroxy-6-Methylpyrimidine-5-Carboxylic Acid is a versatile pyrimidine derivative that serves as a crucial building block in organic synthesis. Its value lies in its bifunctional structure, containing both carboxylic acid and hydroxyl groups on the pyrimidine ring, which makes it an essential intermediate for constructing more complex molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key starting material in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with pyrimidine-based structures, such as certain dihydrofolate reductase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and plant growth regulators, leveraging its heterocyclic core.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for creating novel compound libraries and exploring new therapeutic targets.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and complex organic ligands for catalytic systems.
• Biochemical Studies: Can be utilized as a precursor or analog in biochemical research related to nucleotide metabolism and enzyme inhibition studies.

Basic Information

Product Name	2,4-Dihydroxy-6-Methylpyrimidine-5-Carboxylic Acid
CAS No.	51622-67-4
Molecular Formula	C6H6N2O4
Molecular Weight	170.12 g/mol
Synonyms	6-Methylisoorotic Acid; 6-Methylorotic Acid; 5-Carboxy-2,4-dihydroxy-6-methylpyrimidine; 2,4-Dihydroxy-6-methyl-5-pyrimidinecarboxylic Acid; 6-Methyl-2,4-dihydroxypyrimidine-5-carboxylic Acid; Isoorotic Acid, 6-Methyl-; 6-Methyl-5-carboxyuracil
EINECS	257-286-8

Quality Control

Our 2,4-Dihydroxy-6-Methylpyrimidine-5-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed after each use to minimize exposure to atmospheric moisture and light, which can affect stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.