Description

2-Amino-2,5-Dimethylhexanoic Acid Hydrochloride is a high-purity, non-proteinogenic amino acid derivative supplied as a stable hydrochloride salt. This compound is valued for its role as a critical chiral building block and intermediate in advanced organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in peptide mimetics and small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Peptide Chemistry: Serves as a protected amino acid derivative for the solid-phase and solution-phase synthesis of modified peptides and peptidomimetics.
• Biochemical Research: Employed as a standard or reagent in metabolic pathway studies and enzyme inhibition research.
• Fine Chemical Production: Acts as a building block for synthesizing complex molecules used in flavors, fragrances, and advanced materials.
• Asymmetric Catalysis: Can be utilized as a precursor for chiral ligands or catalysts in enantioselective synthesis.

Basic Information

Product Name	2-Amino-2,5-Dimethylhexanoic Acid Hydrochloride
CAS No.	51606-88-3
Molecular Formula	C8H17NO2 • HCl
Molecular Weight	195.69 g/mol (Free base: 159.23 g/mol)
Synonyms	2-Amino-2,5-dimethylhexanoic acid HCl; 2,5-Dimethylnorleucine hydrochloride; (2R/S)-2-Amino-2,5-dimethylhexanoic acid hydrochloride; 2-Amino-2,5-dimethyl-caproic acid hydrochloride; DL-2-Amino-2,5-dimethylhexanoic acid hydrochloride; 2,5-Dimethyl-2-aminocaproic acid hydrochloride; Norleucine, 2,5-dimethyl-, hydrochloride; UNII-9K2F9F8F8T
EINECS	Contact for details

Quality Control

Our 2-Amino-2,5-Dimethylhexanoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee (or as specified)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.