Description

Proline, 3-Hydroxy-5-Methyl-4-Oxo- (9Ci) CAS NO 51500-05-1 is a specialized proline derivative, a key chiral building block and intermediate in advanced organic synthesis. This compound is valued for its unique functional groups, which enable its use in constructing complex molecular architectures, particularly in pharmaceutical research and development. It serves as a critical precursor for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of novel drug candidates, particularly in protease inhibitor and peptidomimetic development.
• Agrochemical Synthesis: Used as a building block in the production of advanced, biologically active compounds for crop protection.
• Fine Chemical Manufacturing: Serves as a versatile intermediate in custom synthesis and the production of specialty chemicals.
• Biochemical Research: Employed in academic and industrial R&D for studying enzyme-substrate interactions and metabolic pathways.
• Peptide Chemistry: Acts as a modified amino acid residue for introducing specific structural or functional properties into synthetic peptides.
• Catalyst and Ligand Development: Utilized in the design and synthesis of novel chiral catalysts and ligands for asymmetric synthesis.

Basic Information

Product Name	Proline, 3-Hydroxy-5-Methyl-4-Oxo- (9Ci)
CAS No.	51500-05-1
Molecular Formula	C6H9NO4
Molecular Weight	159.14 g/mol
Synonyms	3-Hydroxy-5-methyl-4-oxoproline; 4-Oxo-3-hydroxy-5-methylproline; 5-Methyl-3-hydroxy-4-oxoproline; (2S,3S,5S)-3-Hydroxy-5-methyl-4-oxopyrrolidine-2-carboxylic acid; 3-Hydroxy-5-methyl-4-oxo-L-proline; 4-Oxo-3-hydroxy-5-methyl-L-proline; A derivative of 4-oxoproline
EINECS	Contact for details

Quality Control

Our Proline, 3-Hydroxy-5-Methyl-4-Oxo- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting key specifications are available for every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and our quality commitment ensures a reliable supply for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.