Description

n-(6-Chloro-5-Nitro-4-Oxo-1,4-Dihydropyrimidin-2-Yl)Acetamide is a high-purity pyrimidine derivative, a critical building block in advanced organic synthesis. Its value lies in its functionalized heterocyclic core, which serves as a versatile precursor for creating complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on nucleoside analogs, enzyme inhibitors, and novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel antiviral, anticancer, and antibacterial agents, particularly in the synthesis of modified nucleosides and pyrimidine-based drug candidates.
• Agrochemical Research: Used as a precursor in the synthesis of new herbicides, fungicides, and plant growth regulators that target specific biochemical pathways.
• Biochemical Tool Compound: Serves as a scaffold or inhibitor in biochemical assays to study enzyme mechanisms, particularly those involving dihydropyrimidine dehydrogenase (DPD) or other pyrimidine-metabolizing enzymes.
• Organic Synthesis Building Block: Employed in heterocyclic and medicinal chemistry for constructing complex molecular architectures via reactions at its chloro, nitro, and amide functional groups.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and advanced organic materials.

Basic Information

Product Name	n-(6-Chloro-5-Nitro-4-Oxo-1,4-Dihydropyrimidin-2-Yl)Acetamide
CAS No.	51471-45-5
Molecular Formula	C6H5ClN4O4
Molecular Weight	232.58 g/mol
Synonyms	2-Acetamido-6-chloro-5-nitropyrimidin-4(3H)-one; 2-Acetylamino-6-chloro-5-nitro-4(3H)-pyrimidinone; 6-Chloro-5-nitro-2-(acetylamino)-4(3H)-pyrimidinone; N-(6-Chloro-5-nitro-4-oxo-3,4-dihydropyrimidin-2-yl)acetamide; Acetamide, N-(6-chloro-5-nitro-4-oxo-1,4-dihydropyrimidin-2-yl)-; 51471-45-5; 2-Acetamido-6-chloro-5-nitropyrimidin-4-ol
EINECS	Contact for details

Quality Control

Our n-(6-Chloro-5-Nitro-4-Oxo-1,4-Dihydropyrimidin-2-Yl)Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.