Description

4,6-Diamino-2-Methylthio-5-Pyrimidinesulfonamide is a high-purity, specialized pyrimidine sulfonamide derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of dihydrofolate reductase inhibitors and other therapeutic agents. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality intermediates for complex molecular construction.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of dihydrofolate reductase (DHFR) inhibitors and other specialized drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides that target specific enzymatic pathways.
• Biochemical Research: Serves as a reference standard or building block in enzymatic studies and metabolic pathway investigations.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Material Science: Potential intermediate in the development of advanced organic materials and functional polymers.

Basic Information

Product Name	4,6-Diamino-2-Methylthio-5-Pyrimidinesulfonamide
CAS No.	51461-76-8
Molecular Formula	C5H9N5O2S2
Molecular Weight	235.29 g/mol
Synonyms	2-Methylthio-4,6-diamino-5-pyrimidinesulfonamide; 5-Pyrimidinesulfonamide, 4,6-diamino-2-(methylthio)-; 4,6-Diamino-2-(methylthio)pyrimidine-5-sulfonamide; 2-(Methylthio)-4,6-diamino-5-pyrimidinesulfonamide; NSC 339586; Diaminomethylthiopyrimidinesulfonamide
EINECS	Contact for details

Quality Control

Our 4,6-Diamino-2-Methylthio-5-Pyrimidinesulfonamide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.