Description

Pyrimidine, 4-Chloro-6-Fluoro- (9Ci) is a halogenated pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer agents.
• Agrochemical Synthesis: Serves as a foundational building block for developing new herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Used in the synthesis of specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag in biochemical research and drug discovery platforms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	Pyrimidine, 4-Chloro-6-Fluoro- (9Ci)
CAS No.	51422-01-6
Molecular Formula	C4H2ClFN2
Molecular Weight	132.52 g/mol
Synonyms	4-Chloro-6-fluoropyrimidine; 6-Fluoro-4-chloropyrimidine; 4-Chloro-6-fluoro-1,3-diazine; 4-Chloro-6-fluoropyrimidine (9CI); 4-Chloro-6-fluoro-1H-pyrimidine; Fluoropyrimidine derivative; Halogenated pyrimidine intermediate
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-fluoropyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.