Description

Pyrimidine, 4-Fluoro-2-Methoxy- (9Ci) is a fluorinated and methoxylated pyrimidine derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its ability to introduce both fluorine and methoxy substituents into complex molecular architectures, enabling precise modulation of electronic properties, lipophilicity, and metabolic stability. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel small-molecule therapeutics, particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the synthesis of specialty chemicals, liquid crystals, and organic electronic materials due to its tunable electronic properties.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	Pyrimidine, 4-Fluoro-2-Methoxy- (9Ci)
CAS No.	51421-93-3
Molecular Formula	C5H5FN2O
Molecular Weight	128.10 g/mol
Synonyms	4-Fluoro-2-methoxypyrimidine; 2-Methoxy-4-fluoropyrimidine; 4-Fluoro-2-methoxy-1,3-diazine; 4-Fluoro-2-methoxypyrimidine (9CI); 2-Methoxy-4-fluoropyrimidine; 4-Fluoro-2-methoxy-pyrimidine; 4-Fluoro-2-methoxypyrimidine (9CI)
EINECS	Contact for details

Quality Control

Our Pyrimidine, 4-Fluoro-2-Methoxy- (9Ci) is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring compliance with various standards, and custom purity grades (e.g., >98%, >99%) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.