Description

4-Methylbenzylsulfonyl Chloride is a versatile and reactive organosulfur compound widely used as a key synthetic intermediate. Its primary value lies in its sulfonyl chloride functional group, which readily undergoes nucleophilic substitution reactions to form sulfonamides, sulfonate esters, and other valuable derivatives. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Critical building block for synthesizing sulfonamide-based drugs, including protease inhibitors, diuretics, and antibacterial agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that incorporate sulfonyl functional groups.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and resins with specific thermal or chemical resistance properties.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of sulfonated dyes and organic pigments.
• Material Science Research: Employed in surface modification and the creation of advanced materials with tailored surface properties.
• Chemical Biology & Proteomics: Utilized as a reactive probe or labeling reagent for studying protein function and interactions.

Basic Information

Product Name	4-Methylbenzylsulfonyl Chloride
CAS No.	51419-59-1
Molecular Formula	C8H9ClO2S
Molecular Weight	204.67 g/mol
Synonyms	p-Tolylmethylsulfonyl Chloride; (4-Methylphenyl)methanesulfonyl Chloride; α-Toluenesulfonyl Chloride, 4-methyl-; 4-Methylbenzenemethanesulfonyl Chloride; p-Methylbenzylsulfonyl Chloride; 1-(Chlorosulfonyl)methyl-4-methylbenzene; p-Xylylsulfonyl Chloride
EINECS	Contact for details

Quality Control

Our 4-Methylbenzylsulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay by HPLC, identification by FT-IR, and impurity profiling, to ensure it meets the high-purity standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.