Description

Tizanidine CAS NO 51322-75-9 is a centrally acting skeletal muscle relaxant belonging to the imidazoline chemical class. This high-purity active pharmaceutical ingredient (API) is critical for the formulation of medications that effectively manage spasticity associated with conditions like multiple sclerosis and spinal cord injuries. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of generic and branded neurological therapeutics.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription muscle relaxant tablets and capsules.
• Neurological Disorder Treatment: Formulation of drugs for managing spasticity in patients with multiple sclerosis, spinal cord injury, and other neurological disorders.
• Generic Drug Manufacturing: Sourcing for the production of bioequivalent generic versions of branded tizanidine medications.
• Clinical Research: Utilization in preclinical and clinical studies for new therapeutic applications or dosage forms.
• Reference Standard: Serves as a high-purity chemical standard for analytical testing and quality control in laboratories.
• Contract Manufacturing: Supply to CDMOs (Contract Development and Manufacturing Organizations) for finished dosage form production.

Basic Information

Product Name	Tizanidine
CAS No.	51322-75-9
Molecular Formula	C9H8ClN5S
Molecular Weight	253.71 g/mol
Synonyms	5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine; Zanaflex; Sirdalud; DS-103-282; 4-(2-Benzothiazolyl)-2-imidazolidinone derivative; Tizanidine Hydrochloride (salt form); Tizanidin; Tizanidina
EINECS	Contact for details

Quality Control

Our Tizanidine is manufactured under strict quality systems to meet the rigorous standards required for pharmaceutical intermediates and APIs. We ensure compliance with relevant pharmacopeial guidelines, and every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and supply reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.