Description

3-Trifluoromethyl-1H-Indole is a versatile and high-value fluorinated heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring a reactive indole core and a highly electron-withdrawing trifluoromethyl group, makes it a critical intermediate for creating novel compounds with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients, as well as by manufacturers of specialty materials and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a precursor for functional dyes, liquid crystals, and organic light-emitting diodes (OLEDs) due to its electronic properties.
• Chemical Research: A valuable reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry: Integral component in the synthesis of complex fluorinated molecules for various high-tech applications.

Basic Information

Product Name	3-Trifluoromethyl-1H-Indole
CAS No.	51310-55-5
Molecular Formula	C9H6F3N
Molecular Weight	185.15 g/mol
Synonyms	3-(Trifluoromethyl)-1H-indole; 3-(Trifluoromethyl)indole; 1H-Indole, 3-(trifluoromethyl)-; 3-Trifluoromethylindole; α,α,α-Trifluoro-3-indolylmethane
EINECS	Contact for details

Quality Control

Our 3-Trifluoromethyl-1H-Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support our clients' regulatory needs for pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.