Description

5-Pyrimidinecarboxaldehyde, 4-Amino-6-Chloro-2-Methyl- is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular construction. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Building Block: Employed in custom synthesis and the development of specialty chemicals, dyes, and functional materials.
• Academic & Industrial R&D: Serves as a versatile scaffold for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.

Basic Information

Product Name	5-Pyrimidinecarboxaldehyde, 4-Amino-6-Chloro-2-Methyl-
CAS No.	51290-87-0
Molecular Formula	C6H6ClN3O
Molecular Weight	171.58 g/mol
Synonyms	4-Amino-6-chloro-2-methylpyrimidine-5-carbaldehyde; 4-Amino-6-chloro-2-methyl-5-pyrimidinecarboxaldehyde; 6-Chloro-2-methyl-4-aminopyrimidine-5-carboxaldehyde; 4-Amino-6-chloro-2-methyl-5-formylpyrimidine; 2-Methyl-4-amino-6-chloropyrimidine-5-carboxaldehyde; 5-Formyl-4-amino-6-chloro-2-methylpyrimidine; 4-Amino-6-chloro-2-methylpyrimidine-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxaldehyde, 4-Amino-6-Chloro-2-Methyl- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.