Description

Hydroxyethylthiamine is a synthetic thiamine (vitamin B1) derivative with enhanced stability and bioavailability. This compound is crucial for its role as a key intermediate in the synthesis of advanced pharmaceutical actives and specialized nutritional supplements. It is primarily required by manufacturers in the pharmaceutical, nutraceutical, and fine chemical industries for developing high-value formulations.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of advanced thiamine-based drugs and prodrugs.
• Nutraceutical Formulations: Used in the production of high-potency vitamin B1 supplements and specialized nutritional products.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway research related to thiamine function.
• Veterinary Medicine: Employed in the development of vitamin supplements and therapeutic treatments for animal health.
• Cosmetic Additive: Incorporated into certain skincare formulations for its potential stabilizing and conditioning properties.
• Food Fortification: Used as a stable source of vitamin B1 in the fortification of processed foods and beverages.

Basic Information

Product Name	Hydroxyethylthiamine
CAS No.	51230-37-6
Molecular Formula	C₁₂H₁₈N₄O₃S
Molecular Weight	298.36 g/mol
Synonyms	2-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methylthiazol-3-ium; Thiamine hydroxyethyl derivative; O-(2-Hydroxyethyl)thiamine; Vitamin B1 hydroxyethyl derivative; Hydroxyethyl thiamine; HET; Thiamine 2-hydroxyethyl ether
EINECS	Contact for details

Quality Control

Our Hydroxyethylthiamine is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical and nutritional applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.