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H-Lys-Nh2 2Hcl CAS NO 51127-08-3


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CAS No.:51127-08-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

H-Lys-Nh2 2Hcl is a protected derivative of the essential amino acid L-Lysine, specifically the dihydrochloride salt of Nα-Boc-L-lysine amide. This compound serves as a crucial building block (synthon) in the synthesis of complex peptides and other bioactive molecules, offering precise control over molecular structure. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in peptide-based drug discovery and development.

Application

  • Peptide Synthesis: A key protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS).
  • Pharmaceutical Research: Building block for the development of novel peptide therapeutics, hormones, and enzyme inhibitors.
  • Bioconjugation: Used in the preparation of peptide-protein conjugates for diagnostic and therapeutic applications.
  • Chemical Biology: Tool compound for studying protein-protein interactions and signal transduction pathways.
  • Agrochemical Development: Intermediate in the synthesis of bioactive peptides for crop protection.
  • Cosmetic Peptides: Raw material for synthesizing peptides used in advanced skincare formulations.

Basic Information

Product Name H-Lys-Nh2 2Hcl
CAS No. 51127-08-3
Molecular Formula C11H24N4O3 • 2HCl
Molecular Weight 333.25 g/mol (free base: 260.33)
Synonyms Nα-Boc-L-lysine amide dihydrochloride; Boc-Lys-NH2 • 2HCl; (S)-2-((tert-Butoxycarbonyl)amino)-6-aminohexanamide dihydrochloride; Boc-Lys(NH2)-OH • 2HCl; H-Lys(Boc)-NH2 • 2HCl; N-Boc-L-lysineamide dihydrochloride; Boc-L-Lys-NH2 • 2HCl; tert-Butyloxycarbonyl-L-lysine amide hydrochloride
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Quality Control

Our H-Lys-Nh2 2Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥98.0%
Optical Rotation [α]20/D: +15.0° to +20.0° (c=1 in H2O)
Water Content (KF) ≤1.0%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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