Description

Dobutamine Hydrochloride CAS NO 51062-28-3 is a synthetic catecholamine and a potent, selective β-1 adrenergic receptor agonist. This compound is of critical importance as a key pharmaceutical active ingredient used in the formulation of injectable solutions. It is primarily required by pharmaceutical manufacturers, research institutions, and contract development and manufacturing organizations (CDMOs) involved in cardiovascular therapeutics.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the manufacture of sterile injectable formulations for the short-term treatment of cardiac decompensation.
• Hospital & Clinical Formulations: Used in ready-to-administer solutions for inotropic support in intensive care units (ICUs) and emergency medicine.
• Cardiovascular Research: Serves as a standard reference compound and tool in pharmacological studies of β-adrenergic receptors and cardiac function.
• Contract Manufacturing: Supplied to CDMOs for the production of generic and branded parenteral drugs under cGMP conditions.
• Diagnostic Agent: Utilized in cardiac stress testing and echocardiography to assess heart function and viability.
• Veterinary Medicine: Applied in veterinary cardiology for similar inotropic support in critical animal care.

Basic Information

Product Name	Dobutamine Hydrochloride
CAS No.	51062-28-3
Molecular Formula	C18H23NO3 • HCl
Molecular Weight	337.84 g/mol (Free base: 301.38)
Synonyms	Dobutamine HCl; (±)-Dobutamine Hydrochloride; 4-[2-[[1-Methyl-3-(4-hydroxyphenyl)propyl]amino]ethyl]pyrocatechol Hydrochloride; Dobutrex; Inotrex; (RS)-Dobutamine Hydrochloride; DL-Dobutamine Hydrochloride
EINECS	Contact for details

Quality Control

Our Dobutamine Hydrochloride is manufactured and tested to meet stringent pharmaceutical standards. Quality is assured through a comprehensive battery of tests including identification, assay, impurity profiling, and residual solvent analysis. We provide full traceability and support regulatory filings. Certificates of Analysis (COA) compliant with current pharmacopeial monographs (USP/EP) are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Optical Rotation	Contact for details
Microbial Limits	Complies with USP <61> and <62>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.