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4-o-[2-Amino-6-(Methylamino)-2,3,4,6,7-Pentadeoxy-α-D-Ribo-Heptopyranosyl]-2-Deoxy-D-Streptamine CAS NO 51053-37-3


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CAS No.:51053-37-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-o-[2-Amino-6-(Methylamino)-2,3,4,6,7-Pentadeoxy-α-D-Ribo-Heptopyranosyl]-2-Deoxy-D-Streptamine is a chemically modified aminoglycoside derivative with a complex heptopyranosyl structure. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a synthetic intermediate or a lead compound for novel therapeutics. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of specialized antibiotics, enzyme inhibitors, and other bioactive molecules. The precise control over its stereochemistry and purity is critical for ensuring reproducible results in sensitive biochemical applications.

Application

  • Pharmaceutical Intermediate: Serves as a key synthetic building block in the research and development of novel aminoglycoside-class antibiotics and other therapeutic agents.
  • Biochemical Research: Used as a reference standard or probe in studies investigating bacterial ribosome function, protein synthesis inhibition, and mechanism of action of antimicrobials.
  • Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies aimed at developing new drugs with improved efficacy and reduced toxicity profiles.
  • Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis, carbohydrate chemistry, and glycobiology.
  • Process Development: Utilized in scaling up synthetic routes for complex bioactive molecules within contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name 4-o-[2-Amino-6-(Methylamino)-2,3,4,6,7-Pentadeoxy-α-D-Ribo-Heptopyranosyl]-2-Deoxy-D-Streptamine
CAS No. 51053-37-3
Molecular Formula C14H29N3O6
Molecular Weight 335.40 g/mol
Synonyms 2-Deoxy-4-O-[2-amino-6-(methylamino)-2,3,4,6,7-pentadeoxy-α-D-ribo-heptopyranosyl]streptamine; 4-O-(2-Amino-6-methylamino-2,3,4,6,7-pentadeoxy-α-D-ribo-heptopyranosyl)-2-deoxystreptamine; A derivative of Paromamine; 2-Deoxyparomamine derivative; Antibiotic G-418 related intermediate; Heptopyranosyl streptamine derivative; 51053-37-3; 4-O-[2-Amino-6-(methylamino)-2,3,4,6,7-pentadeoxy-α-D-ribo-heptopyranosyl]-2-deoxy-D-streptamine
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Quality Control

Every batch of our 4-o-[2-Amino-6-(Methylamino)-2,3,4,6,7-Pentadeoxy-α-D-Ribo-Heptopyranosyl]-2-Deoxy-D-Streptamine is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and Mass Spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, supporting research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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