Description

4-(Piperazin-1-Yl)Pyrimidine is a versatile heterocyclic building block and key intermediate in advanced organic synthesis. Its molecular structure, featuring both pyrimidine and piperazine moieties, makes it a critical scaffold for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor research and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand for Catalysis: Can be utilized to create complex ligands for transition metal catalysis in asymmetric synthesis.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-(Piperazin-1-Yl)Pyrimidine
CAS No.	51047-52-0
Molecular Formula	C8H12N4
Molecular Weight	164.21 g/mol
Synonyms	4-(1-Piperazinyl)pyrimidine; 4-Piperazin-1-ylpyrimidine; Pyrimidine, 4-(1-piperazinyl)-; 1-(Pyrimidin-4-yl)piperazine; 4-Pyrimidinylpiperazine; NSC 403914
EINECS	Contact for details

Quality Control

Our 4-(Piperazin-1-Yl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.