Description

Cobalt Deoxyhemoglobin is a metalloprotein derivative where cobalt replaces iron in the heme group of deoxygenated hemoglobin. This compound is a critical biochemical reagent for studying oxygen transport mechanisms, metal-substituted protein behavior, and spectroscopic properties. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical developers engaged in advanced hematology and bioinorganic chemistry studies. The product is supplied as a high-purity material suitable for sensitive analytical and experimental applications.

Application

• Biochemical Research: Serves as a model compound for investigating the structure and function of metal-binding sites in hemoproteins.
• Spectroscopic Studies: Used in UV-Vis, EPR, and magnetic circular dichroism (MCD) spectroscopy to understand electronic transitions in cobalt-substituted porphyrins.
• Diagnostic Development: Acts as a reference standard or key component in the development of assays for blood gas analysis and hemoglobinopathy testing.
• Oxygen Binding Studies: Employed to probe oxygen affinity and cooperative binding effects in artificial oxygen carriers.
• Teaching & Academia: A valuable tool for university-level laboratory courses in bioinorganic chemistry and molecular biology.
• Pharmaceutical R&D: Used in early-stage research for novel therapeutic agents targeting heme-based proteins.

Basic Information

Product Name	Cobalt Deoxyhemoglobin
CAS No.	50935-49-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cobalt(II)-Deoxyhemoglobin; Cobalt-substituted Deoxyhemoglobin; Co-DeoxyHb; Cobalt Protoporphyrin IX Globulin Complex (Deoxy Form); Metallodeoxyhemoglobin (Cobalt); Heme-Cobalt Deoxyglobin Protein
EINECS	Contact for details

Quality Control

Our Cobalt Deoxyhemoglobin is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for research use. Each lot is characterized using advanced analytical techniques including spectroscopy and chromatography. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and relevant physicochemical parameters is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (cold chain). This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability. For long-term storage, consider keeping under an inert atmosphere.

Specification

Item	Specification
Appearance	Dark Brown to Black Lyophilized Powder
Identification (UV-Vis)	Conforms to Reference Spectrum
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Cobalt Content (AAS/ICP)	Reported on COA
Solubility	Soluble in Buffered Aqueous Solutions
Moisture Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.