Description

H-D-Arg(No2)-Ome Hcl is a protected derivative of the amino acid arginine, specifically designed for use in peptide synthesis and advanced biochemical research. This compound is critical for researchers and manufacturers requiring precise control over the guanidino group's reactivity during complex molecular assembly. It serves as a key building block for pharmaceutical R&D, particularly in the development of peptide-based therapeutics, enzyme inhibitors, and diagnostic agents.

Application

• Peptide Synthesis: A crucial protected intermediate for the solid-phase and solution-phase synthesis of arginine-containing peptides.
• Pharmaceutical Research: Used in the discovery and development of novel peptide drugs, enzyme inhibitors, and receptor agonists/antagonists.
• Bioconjugation: Serves as a modified amino acid for creating labeled peptides or protein conjugates for diagnostic and research purposes.
• Chemical Biology: Employed in studying protein-protein interactions and enzyme mechanisms where a protected, non-reactive arginine side chain is required.
• Process Development: Used in scaling up the production of specific peptide sequences for clinical and commercial applications.

Basic Information

Product Name	H-D-Arg(No2)-Ome Hcl
CAS No.	50912-92-0
Molecular Formula	C7H16N5O4 • HCl
Molecular Weight	285.70 g/mol
Synonyms	H-D-Arg(NO2)-OMe • HCl; Methyl N(omega)-nitro-D-argininate hydrochloride; D-Arg(NO2)-OMe • HCl; Methyl (2R)-2-amino-5-[(nitroamino)imino]pentanoate hydrochloride; N(omega)-Nitro-D-arginine methyl ester hydrochloride; (R)-Methyl 2-amino-5-((nitroamino)(imino)methyl)aminopentanoate hydrochloride; D-N(omega)-Nitroarginine methyl ester hydrochloride; NG-Nitro-D-arginine methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our H-D-Arg(No2)-Ome Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material that meets specifications for various research and process development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.