Description

Z-Tyr-Ile-Oh is a protected dipeptide derivative, specifically the C-terminal carboxylic acid of the Z-Tyr-Ile sequence. This compound serves as a crucial building block in solid-phase and solution-phase peptide synthesis, enabling the controlled elongation of peptide chains. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers for the development of novel therapeutic peptides and biochemical tools.

Application

• Pharmaceutical Intermediates: Key raw material for synthesizing longer, biologically active peptide sequences for drug discovery and development.
• Biochemical Research: Used as a standard or reagent in proteomics and enzyme-substrate interaction studies.
• Peptide Library Construction: Essential component in combinatorial chemistry for generating diverse peptide libraries for screening.
• Custom Peptide Synthesis: A fundamental starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke peptides.
• Academic Research: Employed in university and institutional labs for studying peptide structure, function, and synthesis methodologies.

Basic Information

Product Name	Z-Tyr-Ile-Oh
CAS No.	50903-76-9
Molecular Formula	C23H28N2O6
Molecular Weight	428.48 g/mol
Synonyms	N-Carbobenzoxy-L-tyrosyl-L-isoleucine; Z-L-Tyrosyl-L-isoleucine; Z-Tyr-Ile; CBZ-Tyr-Ile-OH; Nα-(Benzyloxycarbonyl)-L-tyrosyl-L-isoleucine; (2S)-2-[[(2S)-2-[[(2S)-2-Benzyloxycarbonylamino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-methylpentanoic acid; Benzyl N-[(2S)-1-[[(1S)-1-carboxy-2-methylbutyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamate
EINECS	Contact for details

Quality Control

Our Z-Tyr-Ile-Oh is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept sealed in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Optical Rotation	-15° to -25° (c=1 in DMF)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.