Description

4-Bromo-2-(Trifluoromethyl)Phenol is a versatile halogenated phenol derivative, distinguished by its bromine and trifluoromethyl substituents which confer unique reactivity and physicochemical properties. This compound is a critical high-purity intermediate for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its specific substitution pattern is essential for modulating electronic and steric effects. It is primarily utilized by pharmaceutical R&D teams, agrochemical formulators, and specialty chemical manufacturers seeking to develop novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing aromatic compounds used in electronic display technologies.
• Polymer Modification: Acts as a functional monomer or additive to introduce flame-retardant or hydrophobic properties into polymer chains.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex biaryl structures in research and development.
• Dye & Pigment Intermediate: Utilized in the manufacture of specialized colorants and photographic chemicals.

Basic Information

Product Name	4-Bromo-2-(Trifluoromethyl)Phenol
CAS No.	50824-04-9
Molecular Formula	C7H4BrF3O
Molecular Weight	241.01 g/mol
Synonyms	2-(Trifluoromethyl)-4-bromophenol; 4-Bromo-α,α,α-trifluoro-o-cresol; 4-Bromo-2-trifluoromethylphenol; 2-Trifluoromethyl-4-bromophenol; Phenol, 4-bromo-2-(trifluoromethyl)-; 4-Bromo-α,α,α-trifluoro-2-cresol; 4-Bromo-2-(trifluoromethyl)phenol; 4-Bromo-2-(trifluoromethyl)hydroxybenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Trifluoromethyl)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.