Description

5-(m-Trifluoromethoxybenzyl)-2,4-Pyrimidinediamine is a high-purity, specialized pyrimidine derivative with a distinct trifluoromethoxybenzyl substitution. This compound is a critical pharmaceutical intermediate and research chemical valued for its unique structural motif that can impart desirable biological activity and metabolic stability. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active pharmaceutical ingredients (APIs) and as a key building block in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly in therapeutic areas targeting enzymes and receptors.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents, leveraging the stability of the trifluoromethoxy group.
• Biochemical Tool Compound: Potential use in developing probes and inhibitors for studying biological pathways in academic and industrial research settings.
• Fine Chemical Synthesis: Employed in custom and contract synthesis for producing complex, high-value specialty chemicals.

Basic Information

Product Name	5-(m-Trifluoromethoxybenzyl)-2,4-Pyrimidinediamine
CAS No.	50823-99-9
Molecular Formula	C12H10F3N3O
Molecular Weight	269.22 g/mol
Synonyms	5-[(3-Trifluoromethoxy)benzyl]pyrimidine-2,4-diamine; 2,4-Diamino-5-[(3-trifluoromethoxy)benzyl]pyrimidine; 5-(3-Trifluoromethoxybenzyl)-2,4-pyrimidinediamine; 5-(m-Trifluoromethoxybenzyl)-2,4-diaminopyrimidine; 2,4-Pyrimidinediamine, 5-[(3-trifluoromethoxy)benzyl]-; 5-(3-(Trifluoromethoxy)benzyl)pyrimidine-2,4-diamine
EINECS	Contact for details

Quality Control

Our 5-(m-Trifluoromethoxybenzyl)-2,4-Pyrimidinediamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.