Description

L-Cysteine,S,S'-1,3-Propanediylbis- (9Ci) is a specialized, high-purity organic compound derived from the amino acid cysteine, serving as a versatile cross-linking agent and biochemical building block. Its primary value lies in its ability to form stable disulfide bridges, which is critical for modifying protein structures, creating advanced biomaterials, and synthesizing complex pharmaceutical intermediates. This product is essential for research and development laboratories, pharmaceutical manufacturers, and biotechnology companies focused on peptide synthesis, drug discovery, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those requiring disulfide bond formation for stability and bioactivity.
• Bioconjugation & Protein Engineering: Used to create cross-linked proteins, antibodies, or peptides to enhance their structural stability, half-life, or functional properties.
• Biomaterial Synthesis: A critical component in developing hydrogels, drug delivery systems, and other polymeric biomaterials that require reversible or responsive cross-linking.
• Research & Development: Serves as a standard or reagent in biochemical research for studying disulfide bond dynamics, redox biology, and enzyme mechanisms.
• Peptide Synthesis: Employed in solid-phase and solution-phase peptide synthesis to introduce specific disulfide constraints into peptide sequences.

Basic Information

Product Name	L-Cysteine,S,S'-1,3-Propanediylbis- (9Ci)
CAS No.	50727-79-2
Molecular Formula	C9H16N2O4S2
Molecular Weight	280.37 g/mol
Synonyms	1,3-Bis(L-cysteinyl)propane; L-Cystine, 1,3-propanediylbis-; 1,3-Propanediylbis-L-cysteine; 1,3-Bis(cysteinyl)propane; NSC 334365; Bis(L-cysteine) propane derivative; 3,3'-Thiodipropionic acid bis(cysteine) derivative
EINECS	Contact for details

Quality Control

Our L-Cysteine,S,S'-1,3-Propanediylbis- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography and spectroscopic methods, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, chiral purity, and related substances. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% L-isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.