Description

3''-Haba Kanamycin A is a chemically modified derivative of the aminoglycoside antibiotic kanamycin A, designed for advanced biochemical and pharmaceutical research. This compound is valued for its specific structural alteration, which is critical for studying antibiotic mechanisms, resistance, and for the development of novel therapeutic agents. It serves as an essential intermediate and reference standard for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors.

Application

• Pharmaceutical Intermediate: Key starting material or building block in the synthesis of novel antibiotic derivatives and more complex therapeutic molecules.
• Biochemical Research: Used as a precise tool to study aminoglycoside antibiotic action, bacterial ribosome interaction, and mechanisms of antimicrobial resistance.
• Reference Standard: Serves as a high-purity analytical standard for quality control (QC) and quality assurance (QA) in pharmaceutical manufacturing and regulatory compliance testing.
• Microbiology Studies: Employed in research to investigate structure-activity relationships (SAR) and to develop assays for antibiotic efficacy screening.
• API Development: Utilized in the research and development phase of new Active Pharmaceutical Ingredients (APIs) targeting bacterial infections.

Basic Information

Product Name	3''-Haba Kanamycin A
CAS No.	50725-25-2
Molecular Formula	C18H36N4O11
Molecular Weight	484.50 g/mol
Synonyms	3''-Hydroxy-4''-aminobutyryl Kanamycin A; 3''-HABA-Kanamycin A; Kanamycin A 3''-HABA derivative; 4-Amino-2-hydroxybutyrylkanamycin A; 3''-NH2(CH2)2CO-Kanamycin A; 3''-(4-Amino-2-hydroxybutanoyl)kanamycin A; Antibiotic NK 1003; NK-1003
EINECS	Contact for details

Quality Control

Our 3''-Haba Kanamycin A is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and stringent controls for residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available upon request to meet the rigorous standards of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.